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PTFE Chemical Resistance Chart

PTFE (Teflon®) is the gold standard for chemical resistance. It handles nearly all chemicals, extreme temperatures, and is the premium choice for gaskets, seals, and linings in demanding applications.

500+ chemicals tested 20°C & 50°C data Premium material
Excellent (A)
Good (B)
Limited (C)
Not Recommended (D)
Showing 0 chemicals
Chemical Concentration 20°C 50°C CAS

PTFE Properties

Full Name Polytetrafluoroethylene
Trade Name Teflon® (DuPont/Chemours)
Max Temperature 260°C (500°F) continuous
Min Temperature -200°C (-328°F)
Density 2.1–2.3 g/cm³
FDA Approved Yes
Friction Lowest of any solid
Cost High (premium)

Common Applications

Seals & Gaskets

O-rings, flange gaskets, valve seats, pump seals

Linings & Coatings

Tank linings, pipe linings, non-stick coatings

Electrical Insulation

Wire insulation, connectors, high-frequency applications

⚠️ Limitations

While PTFE resists most chemicals, it has some limitations:

  • Molten alkali metals (sodium, potassium)
  • Fluorine gas at high temperatures
  • Some fluorinated solvents
  • Cold flow under load (creep)
  • Low wear resistance (soft material)
  • High cost compared to alternatives

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