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Silicone Chemical Resistance Chart

Silicone rubber offers the widest temperature range of any elastomer (-60°C to 230°C) with good chemical resistance to many fluids and excellent biocompatibility.

21 chemicals tested 20°C & 50°C data
22
Excellent (A)
0
Good (B)
0
Limited (C)
1
Not Recommended (D)

The source rates silicone for only 21 chemicals, far fewer than the other materials. A chemical that is missing from this table has not been rated; that does not mean silicone resists it. For seals, compare EPDM, Viton (FPM) and NBR, which the source rates for more than 800 chemicals each.

Resistance by chemical class

Most rows rated A or B
Salts and salt solutions 100 %
Fewest rows rated A or B
Salts and salt solutions 100 %
All rated rows, by rating
A 96 %, B 0 %, C 0 %, D 4 % (23)

Chemical classes were assigned by this site, not by the source. Mixtures and trade products without a clear class are not counted.

Silicone: Resistance by chemical classSalts and salt solutions: A 100 %.Salts and salt solutions (9)Salts and salt solutions: A 100 % (9)A 100 %
A very good resistanceB good resistanceC limited resistanceD not resistant
Share of each rating at 20 °C among the source rows of a class. The number in brackets is the number of rated rows; a row is one chemical at one concentration. Classes with fewer than 8 rated rows are left out.
Showing 23 chemicals
Chemical Concentration 20°C 50°C CAS
Carbon Dioxide Exhaust Gases
Abgase, kohlendioxidhaltig
low concentrationA*–—
Aluminiumhydroxid
—AA21645-51-2
Aluminiumoxid
solidAA1344-28-1
Calciumcarbonat
saturatedAA471-34-1
Calcium Phosphate
Calciumphosphat
aqueousAA7758-87-4
Calcium Phosphate
Calciumphosphat
—AA7758-87-4
Chromic-Sulfuric Acid
Chromschwefelsäure
concentratedDD65272-71-1
Dextrin
aqueousAA9004-53-9
any concentrationAA50-99-7
Chalk
Kreide
—AA—
Lactose
aqueousAA63-42-3
Magnesiumcarbonat
saturatedAA546-93-0
Magnesiumchlorid
aqueousAA7786-30-3
Magnesium Chlorite
Magnesiumchlorit
—AA—
Magnesiumhydroxid
saturatedAA1309-42-8
Natriumchlorid
aqueousAA7647-14-5
Pectin
aqueousAA9000-69-5
Pectin
—AA9000-69-5
Quecksilber
pureAA7439-97-6
Zinc Carbonate
Zinkcarbonat
saturatedAA3486-35-9
Zinkoxid
solidAA1314-13-2
Zinc Phosphate
Zinkphosphat
saturatedAA7779-90-0
Zuckersirup
—AA—

* = estimated rating in the source, given without a temperature. L = risk of pitting or stress-corrosion cracking. Only chemicals with a rating for this material are listed.

Silicone Properties

Full Name Silicone Rubber (VMQ/FVMQ)
Max Temperature 230°C (446°F)
Min Temperature -60°C (-76°F)
Key Property Widest temp range, biocompatible

Common Applications

Medical

Medical tubing, implants, pharmaceutical closures

Food & Beverage

FDA-grade seals, bakeware, food processing

High Temp Seals

Oven seals, exhaust gaskets, lighting seals

Not Recommended For

Silicone may degrade when exposed to:

  • Steam above 150°C (long-term)
  • Concentrated acids and alkalis
  • Hydrocarbon solvents and fuels
  • Ketones and esters

Tip: For fuel and oil resistance, use NBR or Viton. For aggressive chemicals, PTFE is preferred.

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