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HDPE and Acetic Anhydride: Chemical Resistance

High-density polyethylene

Rating

Concentration20 °C50 °CRemark
technical gradeDD

Material comparison at 20 °C

Acetic Anhydride: Material comparison at 20 °CHDPE: D (highlighted); FEP: A; PP: A; PTFE: A; SS 304: A; SS 316: A.FEP: APP: APTFE: ASS 304: ASS 316: AAluminium: BAcetal (POM): BEPDM: CLDPE: CNylon (PA): CViton (FPM): DHDPE: DHDPENBR: DPolycarbonate: DPMP: DPolystyrene: DPolysulfone: DPVC Rigid: DPVC Flexible: DPVDF: DECTFE/ETFE: –PETG: –SAN: –Silicone: –
A very good resistanceB good resistanceC limited resistanceD not resistantno data
Each bar is one material. Taller bars indicate better resistance. The highlighted bar is the current material.

Resistance overview

HDPE is not resistant (D) to Acetic Anhydride at technical grade and should not be used in direct contact. The chemical is expected to cause rapid degradation, which can include dissolution, cracking, severe swelling, or complete structural failure of the material.

Application context

Acetic Anhydride is commonly encountered in laboratory work and surface cleaning. HDPE (High-density polyethylene) is a thermoplastic typically used for tanks, piping, containers and liners. Because Acetic Anhydride is classified as corrosive, the choice of containment material is especially critical to prevent leaks, equipment damage, and safety hazards.

Practical recommendation

HDPE is not recommended for use with Acetic Anhydride. The D rating indicates that the material will suffer rapid and severe degradation, which may include cracking, dissolution, severe swelling, or complete structural failure. Using this combination risks equipment damage, leaks, and potential safety incidents. Consider using PP, FEP, PTFE instead, which are rated A for this chemical and offer reliable long-term performance.

Did you know?

Temperature is often the deciding factor when selecting materials for Acetic Anhydride: even materials rated A at 20 °C may lose performance at elevated temperatures.

Materials rated A or B at 20 °C

Based on the row for technical grade, 20 °C.

Thermoplastics
PP A, Acetal (POM) B
Fluoropolymers
PTFE A, FEP A
Metals
SS 316 A, SS 304 A, Aluminium B

About HDPE

High-density polyethylene resists most aqueous acids, alkalis and salt solutions. Strong oxidising acids, chlorinated solvents and aromatic hydrocarbons attack or swell it. Continuous service is usually limited to about 80 °C.

Rating scale

A rating marked * is an estimate in the source, not a test result. An estimate is given as one value without a temperature.

About this data

The ratings come from the chemical resistance list published by Bürkle GmbH, which compiled them from raw-material manufacturers’ data. They describe laboratory tests on the raw material at 20 °C and 50 °C.

A finished part also sees pressure, mechanical stress, welds and mixtures that a laboratory test does not. Treat the rating as a first filter and test under your own conditions before relying on it.