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PVDF and Dimethyl Sulfoxide (DMSO): Chemical Resistance

Polyvinylidene fluoride

Rating

Concentration20 °C50 °CRemark
concentration not statedC*–

* estimated rating, given in the source without a temperature

Material comparison at 20 °C

Dimethyl Sulfoxide (DMSO): Material comparison at 20 °CPVDF: C (highlighted); Aluminium: A; ECTFE/ETFE: A; FEP: A; HDPE: A; LDPE: A.Aluminium: AECTFE/ETFE: AFEP: AHDPE: ALDPE: APMP: AAcetal (POM): APP: APolystyrene: APTFE: ASS 304: ASS 316: ANylon (PA): BEPDM: CViton (FPM): CPVDF: CPVDFNBR: DPolycarbonate: DPolysulfone: DPVC Rigid: DPETG: –PVC Flexible: –SAN: –Silicone: –
A very good resistanceB good resistanceC limited resistanceD not resistantno data
Each bar is one material. Taller bars indicate better resistance. The highlighted bar is the current material.

Resistance overview

PVDF has limited resistance (C) to Dimethyl Sulfoxide (DMSO) at 20 °C. This indicates that the chemical has a noticeable effect on the material, which may include visible swelling, softening, or a measurable loss of tensile strength. Use is generally limited to short-term or intermittent contact where full structural integrity is not required. The rating remains stable between 20 °C and 50 °C, which means this material can also handle moderately elevated process temperatures without additional risk.

Application context

Dimethyl Sulfoxide (DMSO) is commonly encountered in chemical synthesis and electronics cleaning. PVDF (Polyvinylidene fluoride) is a fluoropolymer typically used for seals, gaskets, valve seats and lined equipment. The compatibility between these two is therefore an important consideration for engineers and procurement teams selecting containment, transfer, or processing equipment.

Practical recommendation

PVDF has limited resistance to Dimethyl Sulfoxide (DMSO) and should only be used for short-term or intermittent contact at ambient temperature. The C rating means the material undergoes noticeable changes — swelling, loss of strength, or surface degradation — that make it unsuitable for permanent installations. For prolonged or continuous exposure, HDPE, LDPE, PMP offer significantly better resistance and are rated A.

Did you know?

The ratings shown here apply to pure Dimethyl Sulfoxide (DMSO) in contact with the base fluoropolymer. In real-world applications, additives, pigments, and fillers in the material can shift resistance in either direction.

Materials rated A or B at 20 °C

Thermoplastics
HDPE A, PP A, LDPE A, Nylon (PA) B, Acetal (POM) A, Polystyrene A, PMP A
Fluoropolymers
PTFE A, FEP A, ECTFE/ETFE A
Metals
SS 316 A, SS 304 A, Aluminium A

About PVDF

PVDF resists acids, halogens and hydrocarbons. Strong bases, amines, ketones and esters attack it. Service temperature is up to about 150 °C.

Rating scale

A rating marked * is an estimate in the source, not a test result. An estimate is given as one value without a temperature.

About this data

The ratings come from the chemical resistance list published by Bürkle GmbH, which compiled them from raw-material manufacturers’ data. They describe laboratory tests on the raw material at 20 °C and 50 °C.

A finished part also sees pressure, mechanical stress, welds and mixtures that a laboratory test does not. Treat the rating as a first filter and test under your own conditions before relying on it.