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Dimethyl Sulfoxide (DMSO) Chemical Resistance

Resistance ratings for 24 plastics, elastomers and metals at 20 °C and 50 °C.

At a glance

Ratings at 20 °C.

Rated A, very good resistance
PTFE, HDPE, PP, SS 316, SS 304, Aluminium, LDPE, FEP, ECTFE/ETFE, Acetal (POM), Polystyrene, PMP (12)
Rated B, good resistance
Nylon (PA) (1)
Rated C, limited resistance
PVDF, EPDM, Viton (FPM) (3)
Rated D, not resistant
PVC Rigid, NBR, Polycarbonate, Polysulfone (4)
No data in the source
Silicone, PVC Flexible, PETG, SAN
Rated lower at 50 °C than at 20 °C
ECTFE/ETFE (A → B), Polystyrene (A → B)

Rating profile by material family

Dimethyl Sulfoxide (DMSO): Rating profile by material familyThermoplastics: 6 A, 1 B, 3 D, 3 no data. Fluoropolymers: 3 A, 1 C. Elastomers: 2 C, 1 D, 1 no data. Metals: 3 A.Thermoplastics (13)Thermoplastics: 6 × A, very good resistance (HDPE, LDPE, PP, PMP, Polystyrene, Acetal (POM))A 6Thermoplastics: 1 × B, good resistance (Nylon (PA))Thermoplastics: 3 × D, not resistant (PVC Rigid, Polycarbonate, Polysulfone)D 3Thermoplastics: 3 × no data (PVC Flexible, SAN, PETG)– 3Fluoropolymers (4)Fluoropolymers: 3 × A, very good resistance (PTFE, FEP, ECTFE/ETFE)A 3Fluoropolymers: 1 × C, limited resistance (PVDF)C 1Elastomers (4)Elastomers: 2 × C, limited resistance (EPDM, Viton (FPM))C 2Elastomers: 1 × D, not resistant (NBR)D 1Elastomers: 1 × no data (Silicone)– 1Metals (3)Metals: 3 × A, very good resistance (SS 316, SS 304, Aluminium)A 3
A very good resistanceB good resistanceC limited resistanceD not resistantno data
Number of materials in each family with each rating at 20 °C.

Effect of temperature, 20 °C to 50 °C

Dimethyl Sulfoxide (DMSO): Effect of temperature, 20 °C to 50 °CPolystyrene A → B; ECTFE/ETFE A → B.ABCDPolystyrene: A at 20 °C, B at 50 °CPolystyreneECTFE/ETFE: A at 20 °C, B at 50 °CECTFE/ETFE
20 °C50 °C
Materials whose rating differs between 20 °C and 50 °C. Materials not shown keep their rating or have no 50 °C value.

Substance

CAS number
67-68-5
Formula
C2H6SO
Hazard symbols in the source
Xi (irritant) (pre-GHS European symbols; check the current safety data sheet)
Name in the source (German)
Dimethylsulfoxid (DMSO)

Resistance table

Material20 °C50 °CRemark
Thermoplastics
HDPEAA
LDPEAA
PPAA
PVC RigidDD
PMPAA
PolystyreneAB
PolycarbonateDD
Acetal (POM)A–
Nylon (PA)B*–
PolysulfoneDD
Fluoropolymers
PTFEA*–
FEPAA
PVDFC*–
ECTFE/ETFEAB
Elastomers
EPDMC*–
Viton (FPM)C*–
NBRD*–
Metals
SS 316A*–
SS 304A*–
AluminiumA*–

* estimated rating, given in the source without a temperature

Not rated in the source, so not in the table: PVC Flexible, SAN, PETG, Silicone

Rating scale

A rating marked * is an estimate in the source, not a test result. An estimate is given as one value without a temperature.

Frequently Asked Questions

Which materials resist Dimethyl Sulfoxide (DMSO) at high concentrations?

The materials with an A rating (resistant) for Dimethyl Sulfoxide (DMSO) at 20 °C are: PTFE, HDPE, PP, SS 316, SS 304, Aluminium, LDPE, FEP. These can generally be used in direct contact.

Which materials should be avoided with Dimethyl Sulfoxide (DMSO)?

Materials rated D (not resistant) for Dimethyl Sulfoxide (DMSO) are: PVC Rigid, NBR, Polycarbonate, Polysulfone. These should not be used in contact with Dimethyl Sulfoxide (DMSO).

Does temperature affect chemical resistance to Dimethyl Sulfoxide (DMSO)?

Yes. 2 of 10 tested materials show a worse rating at 50 °C than at 20 °C for Dimethyl Sulfoxide (DMSO). Materials affected include: ECTFE/ETFE, Polystyrene.

Is PTFE safe for Dimethyl Sulfoxide (DMSO)?

PTFE is rated A for Dimethyl Sulfoxide (DMSO) at 20 °C. A rating of A means resistant, B means limited resistance, C means partly resistant, and D means not resistant.

About this data

The ratings come from the chemical resistance list published by Bürkle GmbH, which compiled them from raw-material manufacturers’ data. They describe laboratory tests on the raw material at 20 °C and 50 °C.

A finished part also sees pressure, mechanical stress, welds and mixtures that a laboratory test does not. Treat the rating as a first filter and test under your own conditions before relying on it.

Chemicals with a similar resistance profile

Same 20 °C rating on the share of materials shown.