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Tetrahydrofuran (THF) Chemical Resistance

Resistance ratings for 24 plastics, elastomers and metals at 20 °C and 50 °C.

At a glance

Ratings at 20 °C.

Rated A, very good resistance
PTFE, SS 316, SS 304, Aluminium, FEP, Nylon (PA), Acetal (POM), PETG (8)
Rated B, good resistance
ECTFE/ETFE (1)
Rated C, limited resistance
HDPE, PP, PVDF, PMP (4)
Rated D, not resistant
PVC Rigid, EPDM, Viton (FPM), NBR, LDPE, Polycarbonate, PVC Flexible, Polystyrene, Polysulfone, SAN (10)
No data in the source
Silicone
Rated lower at 50 °C than at 20 °C
HDPE (C → D), PP (C → D), ECTFE/ETFE (B → C), Acetal (POM) (A → C), PMP (C → D)

Rating profile by material family

Tetrahydrofuran (THF): Rating profile by material familyThermoplastics: 3 A, 3 C, 7 D. Fluoropolymers: 2 A, 1 B, 1 C. Elastomers: 3 D, 1 no data. Metals: 3 A.Thermoplastics (13)Thermoplastics: 3 × A, very good resistance (PETG, Acetal (POM), Nylon (PA))A 3Thermoplastics: 3 × C, limited resistance (HDPE, PP, PMP)C 3Thermoplastics: 7 × D, not resistant (LDPE, PVC Rigid, PVC Flexible, Polystyrene, SAN, Polycarbonate, Polysulfone)D 7Fluoropolymers (4)Fluoropolymers: 2 × A, very good resistance (PTFE, FEP)A 2Fluoropolymers: 1 × B, good resistance (ECTFE/ETFE)B 1Fluoropolymers: 1 × C, limited resistance (PVDF)C 1Elastomers (4)Elastomers: 3 × D, not resistant (EPDM, Viton (FPM), NBR)D 3Elastomers: 1 × no data (Silicone)– 1Metals (3)Metals: 3 × A, very good resistance (SS 316, SS 304, Aluminium)A 3
A very good resistanceB good resistanceC limited resistanceD not resistantno data
Number of materials in each family with each rating at 20 °C.

Effect of temperature, 20 °C to 50 °C

Tetrahydrofuran (THF): Effect of temperature, 20 °C to 50 °CHDPE C → D; PP C → D; PMP C → D; Acetal (POM) A → C; ECTFE/ETFE B → C.ABCDHDPE: C at 20 °C, D at 50 °CHDPEPP: C at 20 °C, D at 50 °CPPPMP: C at 20 °C, D at 50 °CPMPAcetal (POM): A at 20 °C, C at 50 °CAcetal (POM)ECTFE/ETFE: B at 20 °C, C at 50 °CECTFE/ETFE
20 °C50 °C
Materials whose rating differs between 20 °C and 50 °C. Materials not shown keep their rating or have no 50 °C value.

Substance

CAS number
109-99-9
Formula
C4H8O
Hazard symbols in the source
F (flammable), Xi (irritant) (pre-GHS European symbols; check the current safety data sheet)
Flammable
yes
Also listed as
Tetramethylene oxide
Name in the source (German)
Tetrahydrofuran (THF)

Resistance table

Material20 °C50 °CRemark
Thermoplastics
HDPECD
LDPEDD
PPCD
PVC RigidDD
PVC FlexibleDD
PMPCD
PolystyreneDD
SANDD
PolycarbonateDD
PETGA–
Acetal (POM)AC
Nylon (PA)A–
PolysulfoneDD
Fluoropolymers
PTFEA–
FEPAA
PVDFCC
ECTFE/ETFEBC
Elastomers
EPDMDD
Viton (FPM)DD
NBRDD
Metals
SS 316A*–
SS 304A*–
AluminiumAA

* estimated rating, given in the source without a temperature

Not rated in the source, so not in the table: Silicone

Rating scale

A rating marked * is an estimate in the source, not a test result. An estimate is given as one value without a temperature.

Frequently Asked Questions

Which materials resist Tetrahydrofuran (THF) at high concentrations?

The materials with an A rating (resistant) for Tetrahydrofuran (THF) at 20 °C are: PTFE, SS 316, SS 304, Aluminium, FEP, Nylon (PA), Acetal (POM), PETG. These can generally be used in direct contact.

Which materials should be avoided with Tetrahydrofuran (THF)?

Materials rated D (not resistant) for Tetrahydrofuran (THF) are: PVC Rigid, EPDM, Viton (FPM), NBR, LDPE, Polycarbonate, PVC Flexible, Polystyrene. These should not be used in contact with Tetrahydrofuran (THF).

Does temperature affect chemical resistance to Tetrahydrofuran (THF)?

Yes. 5 of 18 tested materials show a worse rating at 50 °C than at 20 °C for Tetrahydrofuran (THF). Materials affected include: HDPE, PP, ECTFE/ETFE, Acetal (POM), PMP.

Is PTFE safe for Tetrahydrofuran (THF)?

PTFE is rated A for Tetrahydrofuran (THF) at 20 °C. A rating of A means resistant, B means limited resistance, C means partly resistant, and D means not resistant.

About this data

The ratings come from the chemical resistance list published by Bürkle GmbH, which compiled them from raw-material manufacturers’ data. They describe laboratory tests on the raw material at 20 °C and 50 °C.

A finished part also sees pressure, mechanical stress, welds and mixtures that a laboratory test does not. Treat the rating as a first filter and test under your own conditions before relying on it.

Chemicals with a similar resistance profile

Same 20 °C rating on the share of materials shown.